Posted under Uncategorized
Today, October 2, 2008, in AP Biology we took notes on the cell cycle. We focused mainly on the phases of cell division. I took my notes on a laptop in order to inject some much needed technology into my otherwise old school day. The class got through all of the phases of cell division, with minimal delays from the slower note takers. The phases of cell division are broken down into two main sections: interphase and mitotic phase. Interphase consists of a first growth phase, a synthesis phase (where the cell duplicates its DNA), and a second growth phase (the cell prepares for division). The mitotic phase consists of prophase, metaphase, anaphase, and telophase. During prophase, the chromatin condenses and appears as sister chromatids. The nuclear envelope breaks down and the centrioles move to opposite poles. The nucleus disappears and the next transitional step, prometaphase, occurs. Prometaphase consists of the mitotic spindle, made of microtubules, attaching to a structure at the centromere of each chromosome called the kintochore.
**A sketch of cell division by falsestartjunkyard on flickr.com
During metaphase the replicated chromosomes line up on the metaphase plate, or the middle line of the cell. The next step is anaphase, in which the sister chromatids separate. The sister chromatids then move to opposite poles of the spindle. The cell begins to lengthen. The next phase of cell division is telophase. The chromosomes go to opposite poles, the daughter nuclei form, and the chromosomes spread out. At that point, the cell division processes are no longer visible under the light microscope. The next step is cytokinesis in which microfilaments condense in the center of the lengthened cell. Cleavage furrows form and the cell splits in two.
What happens when cell division doesn’t work like its supposed to? Malignant cancer cells spread throughout the body because their cell division is unregulated. Cancer cells continue to divide, forming abnormal cells. Cancer is an example of what happens when cell division goes wrong.


